Endocrine Abstracts

Introduction: The incidence of agranulocytosis with thionamide therapy is uncommon, ranging between 0.2 and 0.5 percent. Most reports document agranulocytosis after short duration of high dose Carbimazole in older patients. We report a 32-year-old lady with Graves’ disease who developed neutropaenic sepsis secondary to Carbimazole therapy on 5 mg daily and on treatment for the last 13 months.Case report: Our patient was diagnosed with Graves’s ...

Background: In a research setting, complex behavioural interventions are effective in changing lifestyle behaviour and inducing weight loss. However, these are viewed as requiring a high number of different health care professionals to be successful and thus few are available in the NHS setting. Here we describe how we developed and piloted a complex behavioural intervention for participants with severe morbid obesity.Methods: Using input from a psycholo...

There is limited evidence for the role of screening for Cushing’s syndrome (CS). Patients referred to the specialist medical weight management service at Musgrove Park Hospital have routinely been screened for CS with either an overnight dexamethasone suppression test (ODST) or two 24hour urinary free cortisol (UFC) if evidence of dysglycaemia. We retrospectively analysed the results of all patients referred to the service between 2013–2016. 794 patients were seen as...